Addressing treatment challenges in atopic dermatitis with novel topical therapies
نویسندگان
چکیده
منابع مشابه
Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies.
Atopic dermatitis is a common and chronic, pruritic inflammatory skin condition that can affect all age groups. This evidence-based guideline addresses important clinical questions that arise in its management. In this second of 4 sections, treatment of atopic dermatitis with nonpharmacologic interventions and pharmacologic topical therapies are reviewed. Where possible, suggestions on dosing a...
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Atopic dermatitis (AD) is a complex condition that results from the dynamic interplay between genetic predisposition, skin barrier defects, environmental factors, and a dysfunctional immune system. As a result, AD can be complicated by irritant and allergic contact dermatitis and imbalances in the skin microbiome, which can subsequently exacerbate the severity and complicate the course of preex...
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Atopic dermatitis (AD) is a common, chronic, relapsing, severely pruritic, eczematous skin disease. The mainstays of treatment for AD are topical tacrolimus and topical steroids. Tacrolimus, a calcineurin inhibitor, not only complements existing treatment options but also overcomes some of the drawbacks of topical steroid therapy when given topically and thus meets the long-term needs of patien...
متن کاملAddressing the immunopathogenesis of atopic dermatitis: advances in topical and systemic treatment.
Several immunologic mediators-phosphodiesterase (PDE), interleukin (IL), small molecules, and Janus kinase-have been implicated in the pathogenesis of atopic dermatitis, and evidence has shown that blocking these mediators can help modify the disease process. Several new topical medications have been developed that target the enzyme PDE; crisaborole was recently approved by the US Food and Drug...
متن کاملA review of patient adherence to topical therapies for treatment of atopic dermatitis.
Atopic dermatitis (AD) is one of the most commonly diagnosed dermatologic conditions in the United States. Topical agents are the mainstay of treatment for AD, and when used correctly, these therapies generally are straightforward and efficacious. However, poor adherence to treatment can prevent patients from achieving disease control. This article provides a review of the literature on patient...
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ژورنال
عنوان ژورنال: Journal of Dermatological Treatment
سال: 2016
ISSN: 0954-6634,1471-1753
DOI: 10.1080/09546634.2016.1174765